9EUS
Mpro from SARS-CoV-2 with R298A mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Replicase polyprotein 1a | polymer | 303 | 33333.0 | 2 | UniProt (A0A8B6REU6) Pfam (PF05409) UniProt (by SIFTS) (P0DTD1) | Homo sapiens (human) | ORF1a polyprotein |
| 2 | C, D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: A0A8B6REU6)
| PDB | External Database | Details |
|---|---|---|
| Ala 298 | Arg 3561 | engineered mutation |
| Ala 301 | - | expression tag |
| Ala 302 | - | expression tag |
| Ala 303 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66666.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 66942.3 |
