9EU5
SSX structure of Autotaxin at room temperature
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | polymer | 862 | 98768.2 | 1 | UniProt (Q64610) Pfam (PF01033) Pfam (PF01663) Pfam (PF01223) | Rattus norvegicus (Norway rat) | E-NPP 2,Autotaxin,Extracellular lysophospholipase D,LysoPLD |
| 2 | B (K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB GlyTouCan (G47362BJ) | |||
| 3 | C (A) | 7alpha-hydroxycholesterol | non-polymer | 402.7 | 1 | Chemie (5JK) | |||
| 4 | D, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | E (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 6 | G, H, I, J, K... (A) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
| 7 | AA, BA, CA, DA, P... (A) | IODIDE ION | non-polymer | 126.9 | 15 | Chemie (IOD) | |||
| 8 | EA, FA (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 9 | GA (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 10 | HA (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 11 | IA (A) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A: 1 - 862 (UniProt: Q64610)
| PDB | External Database | Details |
|---|---|---|
| Ala 68 | Val 68 | conflict |
| Ala 410 | Asn 410 | engineered mutation |
| Ala 591 | Arg 591 | conflict |
| Ala 806 | Asn 806 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 98768.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 627.6 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 3498.4 | |
| All* | Total formula weight | 102894.2 |
