9ETI
Complex structure of IL-36R D1-D2 domain with 36R-D481 and BI655130 Fab
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | BI00655130 Fab heavy chain | polymer | 221 | 23783.7 | 1 | Homo sapiens | ||
| 2 | B (L) | BI00655130 Fab light chain | polymer | 215 | 23638.3 | 1 | Homo sapiens | ||
| 3 | C (R) | Interleukin-1 receptor-like 2 | polymer | 207 | 23626.9 | 1 | UniProt (Q9HB29) Pfam (PF13895) | Homo sapiens (human) | IL-36 receptor,IL-36R,Interleukin-1 receptor-related protein 2,IL-1Rrp2,IL1R-rp2 |
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 6 | F (R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G (R) | 4-[3-[[(1~{S})-1-(3-bromophenyl)-3-[2-(2-morpholin-4-ylethoxy)ethylamino]-3-oxidanylidene-propyl]carbamoyl]-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl]-5-cyano-thieno[2,3-b]pyridine-2-carboxylic acid | non-polymer | 751.6 | 1 | Chemie (A1H62) | |||
| 8 | H, I, J (H, L, R) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
R: 20 - 220 (UniProt: Q9HB29)
| PDB | External Database | Details |
|---|---|---|
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71048.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1067.8 | |
| All* | Total formula weight | 72541.1 |
