9ETH

Complex structure of IL-36R D1-D2 domain with 36R-P192 and BI655130 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	BI00655130 Fab heavy chain	polymer	221	23783.7	1		Homo sapiens
2	B (L)	BI00655130 Fab light chain	polymer	215	23638.3	1		Homo sapiens
3	C (P)	ACE-PHE-VAL-GLU-5CW-3PN-TRP-ASP-TYR-VAL-CHG-6G5-SER-GLU-CYS-NH2	polymer	16	2044.1	1		synthetic construct
4	D (R)	Interleukin-1 receptor-like 2	polymer	207	23626.9	1	UniProt (Q9HB29) Pfam (PF13895)	Homo sapiens (human)	IL-36 receptor,IL-36R,Interleukin-1 receptor-related protein 2,IL-1Rrp2,IL1R-rp2
5	E (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	F (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1114.0	1	In PDB GlyTouCan (G43526DV)
7	G, H, I, K, L... (H, L, R)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
8	J (H)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
9	O (R)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
10	Q (R)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
11	R, S, T, U (H, L, P, R)	water	water		18.0	153	Chemie (HOH)

Sequence modifications

R: 20 - 220 (UniProt: Q9HB29)

PDB	External Database	Details
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73092.9
Branched	Number of molecules	2
	Total formula weight	1538.4
Non-Polymers*	Number of molecules	11
	Total formula weight	1104.8
All*	Total formula weight	75736.1

*Water molecules are not included.