9ESH
Structure of a B-state intermediate committed to discard (Bd-I state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | pre-mRNA | polymer | 29 | 9135.3 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 2 | B (2) | U2snRNA | polymer | 186 | 59207.5 | 1 | GenBank (5081) | Schizosaccharomyces pombe (fission yeast) | |
| 3 | C (5) | U5snRNA | polymer | 120 | 38191.4 | 1 | GenBank (5125) | Schizosaccharomyces pombe (fission yeast) | |
| 4 | D (6) | U6snRNA | polymer | 99 | 31864.0 | 1 | GenBank (891582601) | Schizosaccharomyces pombe (fission yeast) | |
| 5 | E (A) | Pre-mRNA-splicing factor spp42 | polymer | 2363 | 274917.8 | 1 | UniProt (O14187) Pfam (PF08082) Pfam (PF08083) Pfam (PF10598) Pfam (PF10597) Pfam (PF10596) Pfam (PF12134) Pfam (PF01398) Pfam (PF08084) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 6 |
| 6 | F (B) | Pre-mRNA-splicing factor cwf10 | polymer | 984 | 111445.3 | 1 | UniProt (O94316) Pfam (PF00009) Pfam (PF03144) Pfam (PF03764) Pfam (PF00679) Pfam (PF16004) | Schizosaccharomyces pombe (fission yeast) | 114 kDa U5 small nuclear ribonucleoprotein component homolog,Complexed with cdc5 protein 10 |
| 7 | G (C) | Pre-mRNA-splicing factor cwf17 | polymer | 340 | 37477.2 | 1 | UniProt (O94620) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 17 |
| 8 | H (D) | Small nuclear ribonucleoprotein Sm D3 | polymer | 97 | 11050.9 | 1 | UniProt (Q9UUC6) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D3,snRNP core protein D3 |
| 9 | I (E) | Small nuclear ribonucleoprotein-associated protein B | polymer | 147 | 15493.0 | 1 | UniProt (Q10163) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-B,Sm protein B,Sm-B,SmB |
| 10 | J (F) | Small nuclear ribonucleoprotein Sm D1 | polymer | 117 | 13115.4 | 1 | UniProt (O42661) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D1,snRNP core protein D1 |
| 11 | K (G) | Small nuclear ribonucleoprotein Sm D2 | polymer | 115 | 13119.3 | 1 | UniProt (O14036) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D2,Complexed with cdc5 protein 9,snRNP core protein D2 |
| 12 | L (H) | Small nuclear ribonucleoprotein E | polymer | 84 | 9702.4 | 1 | UniProt (Q9USZ3) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-E,Sm protein E,Sm-E,SmE |
| 13 | M (I) | Small nuclear ribonucleoprotein F | polymer | 78 | 8667.1 | 1 | UniProt (O59734) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-F,Sm protein F,Sm-F,SmF |
| 14 | N (J) | Small nuclear ribonucleoprotein G | polymer | 77 | 8616.0 | 1 | UniProt (O74966) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-G,Sm protein G,Sm-G,SmG |
| 15 | O (K) | Pre-mRNA-splicing factor prp5 | polymer | 473 | 52492.1 | 1 | UniProt (O13615) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 1,Pre-mRNA-processing protein 5 |
| 16 | P (L) | Pre-mRNA-processing protein 45 | polymer | 557 | 62798.2 | 1 | UniProt (Q09882) Pfam (PF02731) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 13,Transcriptional coregulator snw1 |
| 17 | Q (M) | Pre-mRNA-splicing factor cwf5 | polymer | 354 | 39640.4 | 1 | UniProt (O59800) Pfam (PF21369) Pfam (PF00076) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 5 |
| 18 | R (N) | Pre-mRNA-splicing factor cwf11 | polymer | 1284 | 148532.9 | 1 | UniProt (O94508) Pfam (PF16399) Pfam (PF13087) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 11 |
| 19 | S (O) | Pre-mRNA-splicing factor cwf14 | polymer | 146 | 17122.8 | 1 | UniProt (O74772) Pfam (PF01125) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 14 |
| 20 | T (P) | Pre-mRNA-splicing factor cwf2 | polymer | 388 | 44343.1 | 1 | UniProt (P87126) Pfam (PF16131) Pfam (PF00076) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 2,Pre-mRNA-processing protein 3 |
| 21 | U (Q) | Pre-mRNA-splicing factor cwf15 | polymer | 265 | 30479.0 | 1 | UniProt (P78794) Pfam (PF04889) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 15 |
| 22 | V (R) | Pre-mRNA-splicing factor cwf4 | polymer | 674 | 80964.8 | 1 | UniProt (P87312) Pfam (PF23240) Pfam (PF02184) Pfam (PF23231) Pfam (PF23233) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 4 |
| 23 | W, X, Y, Z (S, T, U, V) | Pre-mRNA-processing factor 19 | polymer | 488 | 54244.0 | 4 | UniProt (O14011) Pfam (PF08606) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 8,RING-type E3 ubiquitin transferase PRP19 |
| 24 | AA (W) | Pre-mRNA-splicing factor cdc5 | polymer | 757 | 86981.3 | 1 | UniProt (P39964) Pfam (PF00249) Pfam (PF11831) | Schizosaccharomyces pombe (fission yeast) | Cell division control protein 5 |
| 25 | BA (X) | Pre-mRNA-splicing factor cwf3 | polymer | 790 | 92759.9 | 1 | UniProt (Q9P7R9) Pfam (PF23233) Pfam (PF23220) Pfam (PF23231) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 3 |
| 26 | CA (Y) | Pre-mRNA-splicing factor syf2 | polymer | 229 | 28037.5 | 1 | UniProt (O59733) Pfam (PF08231) | Schizosaccharomyces pombe (fission yeast) | |
| 27 | DA (Z) | Pre-mRNA-splicing factor cwf7 | polymer | 187 | 21348.2 | 1 | UniProt (Q9USV3) Pfam (PF05700) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 7,Splicing factor 27 |
| 28 | EA (a) | Pre-mRNA-processing factor 17 | polymer | 558 | 63211.3 | 1 | UniProt (O43071) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | |
| 29 | FA (b) | Pre-mRNA-splicing factor cwf21 | polymer | 293 | 34617.8 | 1 | UniProt (O14161) Pfam (PF08312) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 21 |
| 30 | GA (c) | Pre-mRNA-splicing factor cwf22 | polymer | 887 | 102928.4 | 1 | UniProt (Q9P6R9) Pfam (PF02854) Pfam (PF02847) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 22 |
| 31 | HA (d) | Peptidyl-prolyl cis-trans isomerase ppi1 | polymer | 155 | 16884.2 | 1 | UniProt (P87051) Pfam (PF00160) | Schizosaccharomyces pombe (fission yeast) | PPIase ppi1,Cyclophilin ppi1,Rotamase ppi1 |
| 32 | IA (f) | UNK1 | polymer | 22 | 1890.3 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 33 | JA (m) | G-patch domain-containing protein C1486.03 | polymer | 797 | 91791.2 | 1 | UniProt (Q9UTK6) Pfam (PF01585) Pfam (PF07842) | Schizosaccharomyces pombe (fission yeast) | |
| 34 | KA (r) | UNK2 | polymer | 346 | 29464.2 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 35 | LA (y) | Uncharacterized protein C20H4.06c | polymer | 534 | 60850.1 | 1 | UniProt (Q9HE07) Pfam (PF07713) | Schizosaccharomyces pombe (fission yeast) | |
| 36 | MA (z) | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09 | polymer | 647 | 73113.7 | 1 | UniProt (Q9HE06) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) | Schizosaccharomyces pombe (fission yeast) | DEAH-box helicase C20H4.09 |
| 37 | NA, OA, QA, TA (6, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 38 | PA (6) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 39 | RA (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 40 | SA (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 41 | UA, VA, WA, XA, YA... (M, O, P) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 39 |
| Total formula weight | 2039229.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1712.0 | |
| All* | Total formula weight | 2040941.7 |
