9ERZ

Structure of CBL-TKBD bound to Ubiquitin-fused CBLock peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	E3 ubiquitin-protein ligase CBL	polymer	311	36016.6	2	UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762)	Homo sapiens (human)	Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,RING-type E3 ubiquitin transferase CBL,Signal transduction protein CBL
2	B, D (B, D)	Polyubiquitin-C,Ub-fused CBLock peptide	polymer	107	12076.6	2	UniProt (P0CG48) Pfam (PF00240)	Homo sapiens (human)
3	E, F (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	G, H, I, J (A, B, C, D)	water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, C: 47 - 355 (UniProt: P22681)

PDB	External Database	Details
Gly 45	-	expression tag
Ser 46	-	expression tag

B, D: 1 - 74 (UniProt: P0CG48)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D: 75 - 102 (PDB: 9ERZ)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96186.5
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	96266.7

*Water molecules are not included.