9ERY
Co-crystal strucutre of PD-L1 with low molecular weight inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Programmed cell death 1 ligand 1 | polymer | 131 | 14954.1 | 2 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (human) | PD-L1,PDCD1 ligand 1,Programmed death ligand 1,hPD-L1,B7 homolog 1,B7-H1 |
2 | A | 5-[[5-[[2-[bis(fluoranyl)methyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]-2-[(2-hydroxyethylamino)methyl]phenoxy]methyl]pyridine-3-carbonitrile | non-polymer | 573.6 | 1 | Chemie (VVH) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 120 (UniProt: Q9NZQ7)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Ala 121 | - | expression tag |
Ala 122 | - | expression tag |
Ala 123 | - | expression tag |
Leu 124 | - | expression tag |
Glu 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
His 129 | - | expression tag |
His 130 | - | expression tag |
His 131 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 29908.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 669.6 | |
All* | Total formula weight | 30577.8 |