9EQ4

Structure of IgE HMM5 bound to FceRIa cryo-EM class 5

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (H, X)	IgE HMM5 heavy chain	polymer	551	60203.5	2		Homo sapiens
2	B, E (L, Y)	IgE HMM5 light chain	polymer	217	23384.8	2		Homo sapiens
3	C (R)	High affinity immunoglobulin epsilon receptor subunit alpha	polymer	171	19880.1	1	UniProt (P12319) Pfam (PF13927) Pfam (PF13895)	Homo sapiens (human)	Fc-epsilon RI-alpha,FcERI,IgE Fc receptor subunit alpha
4	F, L, M, N (A, G, I, J)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	4	In PDB GlyTouCan (G22768VO)
5	G (B)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G21381MC)
6	H, K (C, F)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G22573RC)
7	I (D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
8	J (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
9	O, P, Q, R, S... (H, X)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	187056.7
Branched	Number of molecules	9
	Total formula weight	7062.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1769.7
All*	Total formula weight	195888.8

*Water molecules are not included.