9EPP
Cryo-EM Structure of Jumping Spider Rhodopsin-1 bound to a Giq heterotrimer
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Kumopsin1 | polymer | 327 | 37282.4 | 1 | UniProt (B1B1U5) Pfam (PF00001) | Hasarius adansoni | |
| 2 | B (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 352 | 40325.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 60 | 6633.6 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | 11,20-Ethanoretinal | non-polymer | 310.5 | 1 | Chemie (A1H6M) |
Sequence modifications
A: 3 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Arg 31 | Ala 31 | engineered mutation |
| Ser 193 | Asp 193 | engineered mutation |
| Ile 194 | Leu 194 | engineered mutation |
| Cys 337 | Asp 337 | engineered mutation |
| Lys 340 | Thr 340 | engineered mutation |
| Thr 342 | Val 342 | engineered mutation |
| Leu 344 | Ile 344 | engineered mutation |
| Gln 345 | Lys 345 | engineered mutation |
| Glu 350 | Asp 350 | engineered mutation |
| Asn 352 | Gly 352 | engineered mutation |
| Val 354 | Phe 354 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121526.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 310.5 | |
| All* | Total formula weight | 121837.2 |
