9EOB
Engineered GH181 sialidase from Akkermansia muciniphila
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | exo-alpha-sialidase | polymer | 580 | 64915.1 | 1 | UniProt (A0A7G6DVF6) Pfam (PF13088) UniProt (by SIFTS) (B2ULI1) | Akkermansia muciniphila ATCC BAA-835 | |
| 2 | B (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 4 | L (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | AA, BA, CA, V, W... (A) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 6 | DA (A) | water | water | 18.0 | 566 | Chemie (HOH) |
Sequence modifications
A: 24 - 595 (UniProt: A0A7G6DVF6)
| PDB | External Database | Details |
|---|---|---|
| Ala 349 | His 349 | conflict |
| Tyr 350 | Gln 350 | conflict |
| Val 477 | Ala 477 | conflict |
| Lys 516 | Arg 516 | conflict |
| Leu 596 | - | expression tag |
| Glu 597 | - | expression tag |
| His 598 | - | expression tag |
| His 599 | - | expression tag |
| His 600 | - | expression tag |
| His 601 | - | expression tag |
| His 602 | - | expression tag |
| His 603 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64915.1 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 1565.7 | |
| All* | Total formula weight | 66480.8 |
