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9EOA

Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate and PCNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Fanconi-associated nuclease 1polymer63672629.71UniProt (Q9Y2M0)
Pfam (PF21315)
Pfam (PF21169)
Pfam (PF21170)
Pfam (PF08774)
Homo sapiens (human)FANCD2/FANCI-associated nuclease 1,hFAN1,Myotubularin-related protein 15
2B
(B)
DNA (continuous)polymer4012154.71Homo sapiens
3C
(C)
DNA (pre-nick)polymer288618.51Homo sapiens
4D
(D)
DNA (post-nick)polymer216554.21Homo sapiens
5E, F, G
(F, G, H)
Proliferating cell nuclear antigenpolymer25628278.33UniProt (P12004)
Pfam (PF00705)
Pfam (PF02747)
Homo sapiens (human)PCNA,Cyclin
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight184792.1
All*Total formula weight184792.1
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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