9EMJ
SARS-CoV-2 methyltransferase nsp10-16 in complex with Toyocamycin and m7GpppA (Cap0-analog)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 2'-O-methyltransferase nsp16 | polymer | 303 | 33912.8 | 1 | UniProt (P0DTD1) Pfam (PF06460) In PDB | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 16,nsp16 |
2 | B | Non-structural protein 10 | polymer | 140 | 14860.0 | 1 | UniProt (P0DTD1) Pfam (PF09401) In PDB | Severe acute respiratory syndrome coronavirus 2 | nsp10,Growth factor-like peptide,GFL |
3 | A | 4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | non-polymer | 291.3 | 1 | Chemie (TO1) | |||
4 | A | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 1 | Chemie (GTA) | |||
5 | A | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 1 | Chemie (MGP) | |||
6 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
7 | B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
8 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
B: 4254 - 4392 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ser 6797 | - | expression tag |
Asn 6798 | - | expression tag |
Glu 7097 | - | expression tag |
Asn 7098 | - | expression tag |
Leu 7099 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 4253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 48772.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1871.9 | |
All* | Total formula weight | 50644.7 |