9EJD

Crystal structure of HLA-B*07:02 with the 9-mer TP53 mutant peptide SPILTIITL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	HLA class I histocompatibility antigen, B alpha chain	polymer	277	32190.3	2	UniProt (P01889) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	Human leukocyte antigen B,HLA-B
2	B, E (B, E)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C, F (C, F)	Peptide from Cellular tumor antigen p53	polymer	9	970.2	2	UniProt (P04637)	Homo sapiens	Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
4	G, H, I, IA, JA... (A, D, B, E)	1,2-ETHANEDIOL	non-polymer		62.1	14	Chemie (EDO)
5	AA, J, K, L, NA... (D, A, E, B)	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
6	BA, CA, DA, EA, FA... (D, A, E, B)	CHLORIDE ION	non-polymer		35.5	11	Chemie (CL) PubChem (312)
7	HA, N (D, A)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI) PubChem (934)
8	UA, VA, WA, XA, YA... (A, B, C, D, E...)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

A, D: 1 - 276 (UniProt: P01889)

PDB	External Database	Details
Met 0	-	initiating methionine

B, E: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

C, F: 1 - 9 (UniProt: P04637)

PDB	External Database	Details
Ser 1	Arg 249	variant

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	90079.8
Non-Polymers*	Number of molecules	40
	Total formula weight	2625.1
All*	Total formula weight	92704.9

*Water molecules are not included.