9EI9
Cryo-EM structure of 5E10 Fab in complex with H3 influenza Victoria 2011 HA trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E (B, C, G) | Hemagglutinin HA1 | polymer | 334 | 37546.4 | 3 | UniProt (L0HR89) Pfam (PF00509) UniProt (by SIFTS) (A0A5P1MU07) | Influenza A virus (A/Victoria/361/2011(H3N2)) | |
| 2 | C, D, F (E, F, I) | Hemagglutinin HA2 | polymer | 222 | 25234.1 | 3 | UniProt (L0HR89) Pfam (PF00509) UniProt (by SIFTS) (A0A3G2CC79) | Influenza A virus (A/Victoria/361/2011(H3N2)) | |
| 3 | G, I (A, H) | 5E10 Fab Heavy chain | polymer | 123 | 13463.0 | 2 | Mus musculus (mouse) | ||
| 4 | H, J (D, J) | 5E10 Fab Light chain | polymer | 111 | 11616.0 | 2 | Mus musculus (mouse) | ||
| 5 | K, M, N, P (K, M, N, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | L, O, Q (L, O, Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 7 | AA, BA, CA, DA, EA... (C, E, F, G, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) |
Sequence modifications
B, C, G: 1 - 329 (UniProt: L0HR89)
E, F, I: 1 - 176 (UniProt: L0HR89)
| PDB | External Database | Details |
|---|---|---|
| Cys 30 | Thr 46 | conflict |
| Arg 330 | - | expression tag |
| Arg 331 | - | expression tag |
| Arg 332 | - | expression tag |
| Arg 333 | - | expression tag |
| Arg 334 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Cys 47 | Gln 392 | conflict |
| Ser 177 | - | expression tag |
| Gly 178 | - | expression tag |
| Arg 179 | - | expression tag |
| Leu 180 | - | expression tag |
| Val 181 | - | expression tag |
| Pro 182 | - | expression tag |
| Arg 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Ser 185 | - | expression tag |
| Pro 186 | - | expression tag |
| Gly 187 | - | expression tag |
| Ser 188 | - | expression tag |
| Gly 189 | - | expression tag |
| Tyr 190 | - | expression tag |
| Ile 191 | - | expression tag |
| Pro 192 | - | expression tag |
| Glu 193 | - | expression tag |
| Ala 194 | - | expression tag |
| Pro 195 | - | expression tag |
| Arg 196 | - | expression tag |
| Asp 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Gln 199 | - | expression tag |
| Ala 200 | - | expression tag |
| Tyr 201 | - | expression tag |
| Val 202 | - | expression tag |
| Arg 203 | - | expression tag |
| Lys 204 | - | expression tag |
| Asp 205 | - | expression tag |
| Gly 206 | - | expression tag |
| Glu 207 | - | expression tag |
| Trp 208 | - | expression tag |
| Val 209 | - | expression tag |
| Leu 210 | - | expression tag |
| Leu 211 | - | expression tag |
| Ser 212 | - | expression tag |
| Thr 213 | - | expression tag |
| Phe 214 | - | expression tag |
| Leu 215 | - | expression tag |
| Gly 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 238499.6 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3457.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4424.2 | |
| All* | Total formula weight | 246381.0 |
