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9EHD

Crystal structure of N-SH2 domain of SHP2 bound to GAB1 tyrosine phosphorylated peptide (624-633) QVEpYLDLDLD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 1 of Tyrosine-protein phosphatase non-receptor type 11polymer10912207.61UniProt (Q06124)
Pfam (PF00017)
Homo sapiens (human)Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
2B
(B)
Phosphorylated peptide from GRB2-associated-binding protein 1polymer101302.31UniProt (Q13480)Homo sapiensGRB2-associated binder 1,Growth factor receptor bound protein 2-associated protein 1
3C, D
(A, B)
waterwater18.041Chemie (HOH)
Sequence modifications
A: 1 - 106 (UniProt: Q06124)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight13509.9
All*Total formula weight13509.9
*Water molecules are not included.

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PDB entries from 2026-01-28

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