9EGM
Human BEST1 bound to GABA in an open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Bestrophin-1 | polymer | 406 | 47416.4 | 5 | UniProt (O76090) Pfam (PF01062) | Homo sapiens (human) | TU15B,Vitelliform macular dystrophy protein 2 |
| 2 | F, J, M, P, T (A, B, C, D, E) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 3 | G, K, N, Q, R (A, B, C, D, E) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | H, I, L, O, S (A, B, C, D, E) | GAMMA-AMINO-BUTANOIC ACID | non-polymer | 103.1 | 5 | Chemie (ABU) | |||
| 5 | U, V, W, X, Y (A, B, C, D, E) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 398 (UniProt: O76090)
| PDB | External Database | Details |
|---|---|---|
| Ser 399 | - | expression tag |
| Asn 400 | - | expression tag |
| Ser 401 | - | expression tag |
| Leu 402 | - | expression tag |
| Glu 403 | - | expression tag |
| Val 404 | - | expression tag |
| Leu 405 | - | expression tag |
| Phe 406 | - | expression tag |
| Gln 407 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 237082.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 893.3 | |
| All* | Total formula weight | 237975.5 |
