9EG9
Crystal structure of human dihydroorotate dehydrogenase in complex with lapachol
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 368 | 39943.6 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D, E, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | H, J, K (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | I (A) | 2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione | non-polymer | 242.3 | 1 | Chemie (A1BIJ) | |||
| 8 | L (A) | water | water | 18.0 | 245 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Ser 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39943.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1478.2 | |
| All* | Total formula weight | 41421.8 |
