9EF9
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with three DILP5, asymmetric conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Insulin-like receptor | polymer | 2144 | 240078.1 | 2 | UniProt (P09208) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF07714) | Drosophila melanogaster (fruit fly) | dIR,dInr,Insulin receptor homolog,dIRH,Receptor protein-tyrosine kinase InR |
| 2 | C, E, G (C, E, G) | DILP5 A-chain | polymer | 25 | 2795.1 | 3 | UniProt (Q7KUD5) | Drosophila melanogaster | |
| 3 | D, F, H (D, F, H) | DILP5 B-chain | polymer | 28 | 3018.6 | 3 | UniProt (Q7KUD5) Pfam (PF00049) | Drosophila melanogaster | dILP5,Insulin-related peptide 5 |
| 4 | AA, I, J, K, L... (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 19 | Chemie (NAG) |
Sequence modifications
C, E, G: 1 - 25 (UniProt: Q7KUD5)
| PDB | External Database | Details |
|---|---|---|
| Asn 12 | Lys 95 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 497597.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 4203.0 | |
| All* | Total formula weight | 501800.2 |
