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9EF5

Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with one DILP2, asymmetric conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Insulin-like receptorpolymer2144240078.12UniProt (P09208)Drosophila melanogaster (fruit fly)dIR,dInr,Insulin receptor homolog,dIRH,Receptor protein-tyrosine kinase InR
2C
(C)
DILP2 B-chainpolymer242750.21UniProt (Q9VT51)Drosophila melanogaster
3D
(D)
DILP2 A-chainpolymer263025.61UniProt (Q9VT51)Drosophila melanogaster
4E, F, G, H, I...
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.216Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight485931.9
Non-Polymers*Number of molecules16
Total formula weight3539.3
All*Total formula weight489471.3
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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