9EF1
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with one DILP1, asymmetric conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DILP1 B-chain | polymer | 41 | 4243.9 | 1 | UniProt (Q9VT50) | Drosophila melanogaster | dILP1,Insulin-related peptide 1 |
| 2 | B (D) | DILP1 A-chain | polymer | 27 | 3025.6 | 1 | UniProt (Q9VT50) | Drosophila melanogaster | |
| 3 | C, D (A, B) | Insulin-like receptor | polymer | 2144 | 240078.1 | 2 | UniProt (P09208) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF07714) | Drosophila melanogaster (fruit fly) | dIR,dInr,Insulin receptor homolog,dIRH,Receptor protein-tyrosine kinase InR |
| 4 | E, F, G, H, I... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
C: 1 - 41 (UniProt: Q9VT50)
| PDB | External Database | Details |
|---|---|---|
| Lys 41 | Arg 70 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 487425.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 490080.1 |
