9EDR

Tubulin Cofactors D,E,G,C and Tubulin complex -- TBCC N Terminus Bound to Tubulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	Chromosome instability protein 1	polymer	1021	117739.4	1	UniProt (P40987) Pfam (PF23579) Pfam (PF25767)	Saccharomyces cerevisiae (brewer's yeast)
2	B (G)	GTP-binding protein CIN4	polymer	191	22081.7	1	UniProt (P39110) Pfam (PF00025)	Saccharomyces cerevisiae (brewer's yeast)	Chromosome instability protein 4
3	C (A)	Tubulin alpha-1A chain	polymer	451	50121.3	1	UniProt (P02550) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Alpha-tubulin 1,Tubulin alpha-1 chain
4	D (B)	Tubulin beta chain	polymer	445	49907.8	1	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Beta-tubulin
5	E (C)	Tubulin-specific chaperone C	polymer	268	30750.8	1	UniProt (P46670)	Saccharomyces cerevisiae (brewer's yeast)	Chromosome instability protein 2,Tubulin-folding cofactor C
6	F (I)	iiH5 alphaRep	polymer	170	18866.6	1		Escherichia coli
7	G (E)	Protein PAC2	polymer	421	38682.6	1	UniProt (P39937)	Saccharomyces cerevisiae (brewer's yeast)
8	H, I (G, A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
9	J (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)

Sequence modifications

D: 1 - 1014 (UniProt: P40987)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

G: 1 - 191 (UniProt: P39110)

PDB	External Database	Details
Leu 73	Gln 73	engineered mutation

E: 8 - 404 (PDB: 9EDR)
E: 422 - 518 (UniProt: P39937)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	328150.2
Non-Polymers*	Number of molecules	3
	Total formula weight	1489.6
All*	Total formula weight	329639.8

*Water molecules are not included.