9EDC
Reset Type-I Protein Kinase A Holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40737.3 | 1 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (human) | PKA C-alpha |
| 2 | B (B) | cAMP-dependent protein kinase type I-alpha regulatory subunit | polymer | 421 | 47415.4 | 1 | UniProt (P00514) Pfam (PF02197) Pfam (PF00027) | Bos taurus (domestic cattle) | |
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A: 1 - 350 (UniProt: P17612)
B: 0 - 379 (UniProt: P00514)
| PDB | External Database | Details |
|---|---|---|
| Thr 32 | Ser 33 | conflict |
| Ser 34 | Ala 35 | conflict |
| Gln 39 | His 40 | conflict |
| Asp 44 | Glu 45 | conflict |
| Ser 65 | Thr 66 | conflict |
| Ala 124 | Pro 125 | conflict |
| Thr 348 | Ser 349 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -41 | - | initiating methionine |
| Arg -40 | - | expression tag |
| Gly -39 | - | expression tag |
| Ser -38 | - | expression tag |
| His -37 | - | expression tag |
| His -36 | - | expression tag |
| His -35 | - | expression tag |
| His -34 | - | expression tag |
| His -33 | - | expression tag |
| His -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Met -30 | - | expression tag |
| Ala -29 | - | expression tag |
| Ser -28 | - | expression tag |
| Met -27 | - | expression tag |
| Thr -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gln -23 | - | expression tag |
| Gln -22 | - | expression tag |
| Met -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Arg -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Leu -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Arg -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Thr -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88152.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 507.2 | |
| All* | Total formula weight | 88659.9 |
