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9ED7

Active state of mTOR on membrane

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase mTORpolymer2549289258.01UniProt (P42345)
Pfam (PF11865)
Pfam (PF02259)
Pfam (PF08771)
Pfam (PF00454)
Pfam (PF02260)
Homo sapiens (human)FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1
2B
(B)
Target of rapamycin complex subunit LST8polymer32635910.11UniProt (Q9BVC4)
Pfam (PF00400)
Homo sapiens (human)TORC subunit LST8,G protein beta subunit-like,Protein GbetaL,Mammalian lethal with SEC13 protein 8,mLST8
3C
(L)
GTP-binding protein Rhebpolymer18420519.41UniProt (Q15382)
Pfam (PF00071)
Homo sapiens (human)Ras homolog enriched in brain
4D
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
5E, F, I
(A, L)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
6G
(A)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
7H
(L)
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATEnon-polymer539.21Chemie (GSP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight345687.5
Non-Polymers*Number of molecules6
Total formula weight1778.4
All*Total formula weight347465.9
*Water molecules are not included.

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PDB entries from 2025-10-29

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