9ED1
Cryo-EM structure of the human KCa3.1/calmodulin channel in complex with Ca2+ and 1,4-dihydropyridine (DHP-103)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (A, B, C, D) | Intermediate conductance calcium-activated potassium channel protein 4 | polymer | 378 | 42598.6 | 4 | UniProt (O15554) Pfam (PF03530) Pfam (PF07885) Pfam (PF02888) | Homo sapiens (human) | SKCa 4,SKCa4,hSK4,Gardos channel,IKCa1,hIK1,KCa3.1,Putative Gardos channel,hKCa4 |
2 | E, F, G, H (E, F, G, H) | Calmodulin-1 | polymer | 145 | 16406.0 | 4 | UniProt (P0DP29) Pfam (PF13499) | Rattus norvegicus (Norway rat) | |
3 | I, J, K, L, M (A, B) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
4 | N, O, P, Q, R... (E, F, G, H) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 236018.5 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 676.4 | |
All* | Total formula weight | 236695.0 |