9ECV
CryoEM Structure Of Respiratory Syncytial Virus Polymerase in complex with Novel Non-Nucleoside Inhibitor Compound 16
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase L | polymer | 2201 | 254482.8 | 1 | UniProt (P28887) Pfam (PF00946) Pfam (PF14318) Pfam (PF14314) | human respiratory syncytial virus | Protein L,Large structural protein,Replicase,Transcriptase |
| 2 | B, C, D, E (B, C, D, E) | Phosphoprotein | polymer | 256 | 29032.8 | 4 | UniProt (P03421) Pfam (PF02478) | human respiratory syncytial virus | Protein P |
| 3 | F (G) | Compound 16 | polymer | 3 | 513.1 | 1 | synthetic construct | ||
| 4 | G, H (A, G) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 2165 (UniProt: P28887)
B, C, D, E: 1 - 241 (UniProt: P03421)
| PDB | External Database | Details |
|---|---|---|
| Met -35 | - | initiating methionine |
| Gly -34 | - | expression tag |
| Ser -33 | - | expression tag |
| Trp -32 | - | expression tag |
| Ser -31 | - | expression tag |
| His -30 | - | expression tag |
| Pro -29 | - | expression tag |
| Gln -28 | - | expression tag |
| Phe -27 | - | expression tag |
| Glu -26 | - | expression tag |
| Lys -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Ser -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Trp -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| Pro -14 | - | expression tag |
| Gln -13 | - | expression tag |
| Phe -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 171 | Ile 171 | variant |
| Lys 242 | - | expression tag |
| Gly 243 | - | expression tag |
| Glu 244 | - | expression tag |
| Asn 245 | - | expression tag |
| Leu 246 | - | expression tag |
| Tyr 247 | - | expression tag |
| Phe 248 | - | expression tag |
| Gln 249 | - | expression tag |
| Gly 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| His 254 | - | expression tag |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 371127.2 | |
| All* | Total formula weight | 371127.2 |
