9ECJ

Human P2RY8 bound to S-geranylgeranyl-L-glutathione in complex with miniG13

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	P2Y purinoceptor 8	polymer	384	43194.5	1	UniProt (Q86VZ1) Pfam (PF00001)	Homo sapiens (human)	P2Y8
2	B (C)	Guanine nucleotide-binding protein subunit alpha-13	polymer	240	27776.8	1	UniProt (Q14344) Pfam (PF00503)	Homo sapiens	G alpha-13,G-protein subunit alpha-13
3	C (D)	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	370	40786.6	1	UniProt (P62873) Pfam (PF00400)	Homo sapiens (human)	Transducin beta chain 1
4	D (B)	L-gamma-glutamyl-S-[(2Z,6E)-3,7,15-trimethyl-11-methylidenehexadeca-2,6,14-trien-1-yl]-L-cysteinylglycine	non-polymer		579.8	1	Chemie (A1BIG)

Sequence modifications

B: 1 - 359 (UniProt: Q86VZ1)

PDB	External Database	Details
Phe -8	-	expression tag
Ala -7	-	expression tag
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Gly 360	-	expression tag
Ser 361	-	expression tag
Ser 362	-	expression tag
Gly 363	-	expression tag
Leu 364	-	expression tag
Glu 365	-	expression tag
Val 366	-	expression tag
Leu 367	-	expression tag
Phe 368	-	expression tag
Gln 369	-	expression tag
Gly 370	-	expression tag
Pro 371	-	expression tag
Gly 372	-	expression tag
Gly 373	-	expression tag
Ser 374	-	expression tag
Gly 375	-	expression tag

C: 16 - 202 (PDB: 9ECJ)
C: 203 - 367 (UniProt: Q14344)

PDB	External Database	Details
Asp 248	Ser 248	conflict
Asp 251	Glu 251	conflict
Asp 261	Ile 271	conflict
Ala 345	Ile 355	conflict
Ile 348	Val 358	conflict

D: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Met -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
Leu -22	-	expression tag
Glu -21	-	expression tag
Val -20	-	expression tag
Leu -19	-	expression tag
Phe -18	-	expression tag
Gln -17	-	expression tag
Gly -16	-	expression tag
Pro -15	-	expression tag
Glu -14	-	expression tag
Asp -13	-	expression tag
Gln -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Pro -9	-	expression tag
Arg -8	-	expression tag
Leu -7	-	expression tag
Ile -6	-	expression tag
Asp -5	-	expression tag
Gly -4	-	expression tag
Lys -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	111757.8
Non-Polymers*	Number of molecules	1
	Total formula weight	579.8
All*	Total formula weight	112337.6

*Water molecules are not included.