9ECF
Crystal structure of the hERbeta LBD complexed with androstenediol and SRC 2-2 peptide (crystal form 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (E, F, A, B, I...) | Estrogen receptor beta | polymer | 247 | 28069.2 | 8 | UniProt (Q92731) Pfam (PF00104) | Homo sapiens (human) | ER-beta,Nuclear receptor subfamily 3 group A member 2 |
| 2 | C, D, G, H, K... (G, H, C, D, K...) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 8 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | Q, R, S, T, U... (E, F, A, B, I...) | (3alpha,8alpha,17beta)-androst-5-ene-3,17-diol | non-polymer | 290.4 | 8 | Chemie (B81) PubChem (10634) PubChem (44135378) PubChem (16395906) PubChem (44330802) PubChem (44403724) PubChem (102192) PubChem (223407) PubChem (1778953) PubChem (1778952) PubChem (57273709) PubChem (59994410) PubChem (67406080) PubChem (54217348) PubChem (968807) PubChem (968809) PubChem (968810) PubChem (67406505) PubChem (968808) PubChem (117748646) PubChem (124892990) PubChem (9814541) PubChem (124903284) PubChem (9965812) PubChem (11872753) PubChem (9904098) PubChem (9922062) PubChem (10062826) PubChem (124303392) PubChem (11872752) PubChem (11872754) PubChem (13215812) PubChem (13215813) PubChem (124892989) PubChem (124903283) PubChem (134128060) PubChem (141819629) PubChem (142954816) PubChem (143269645) PubChem (154292003) PubChem (163018790) PubChem (163018791) PubChem (163889246) PubChem (172012091) | |||
| 4 | AA, BA, CA, DA, EA... (G, A, B, C, D...) | water | water | 18.0 | 632 | Chemie (HOH) |
Sequence modifications
E, F, A, B, I, J, M, N: 261 - 500 (UniProt: Q92731)
| PDB | External Database | Details |
|---|---|---|
| Met 254 | - | expression tag |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
| His 257 | - | expression tag |
| His 258 | - | expression tag |
| His 259 | - | expression tag |
| His 260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 237192.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2323.5 | |
| All* | Total formula weight | 239516.2 |
