9ECF

Crystal structure of the hERbeta LBD complexed with androstenediol and SRC 2-2 peptide (crystal form 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, F, I... (E, F, A, B, I...)	Estrogen receptor beta	polymer	247	28069.2	8	UniProt (Q92731)	Homo sapiens (human)	ER-beta,Nuclear receptor subfamily 3 group A member 2
2	C, D, G, H, K... (G, H, C, D, K...)	Nuclear receptor coactivator 2	polymer	13	1579.9	8	UniProt (Q15596)	Homo sapiens	NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3	Q, R, S, T, U... (E, F, A, B, I...)	(3alpha,8alpha,17beta)-androst-5-ene-3,17-diol	non-polymer		290.4	8	Chemie (B81)
4	AA, BA, CA, DA, EA... (G, A, B, C, D...)	water	water		18.0	632	Chemie (HOH)

Sequence modifications

E, F, A, B, I, J, M, N: 261 - 500 (UniProt: Q92731)

PDB	External Database	Details
Met 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	237192.7
Non-Polymers*	Number of molecules	8
	Total formula weight	2323.5
All*	Total formula weight	239516.2

*Water molecules are not included.