9EC7

Cryo-EM structure of avian tetrameric IgA-Fc/J chain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Immunoglobulin heavy chain alpha	polymer	343	37401.5	8	UniProt (A0A8B9SH23)	Anas platyrhynchos (mallard)
2	I (J)	Joining chain of multimeric IgA and IgM	polymer	138	15800.7	1	UniProt (A0A8B9TFQ9)	Anas platyrhynchos (mallard)
3	J, K, M, N, O... (L, M, P, Q, K...)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	6	In PDB GlyTouCan (G15407YE)
4	L (O)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)

Sequence modifications

A, B, C, D, E, F, G, H: 107 - 420 (UniProt: A0A8B9SH23)

PDB	External Database	Details
His 98	-	expression tag
His 99	-	expression tag
His 100	-	expression tag
His 101	-	expression tag
His 102	-	expression tag
His 103	-	expression tag
Gly 104	-	expression tag
Ser 105	-	expression tag
Ile 106	-	expression tag
Ala 209	Pro 258	conflict
Gly 421	-	expression tag
Lys 422	-	expression tag
Pro 423	-	expression tag
Thr 424	-	expression tag
Gln 425	-	expression tag
Val 426	-	expression tag
Asn 427	-	expression tag
Val 428	-	expression tag
Ser 429	-	expression tag
Val 430	-	expression tag
Val 431	-	expression tag
Leu 432	-	expression tag
Ser 433	-	expression tag
Asp 434	-	expression tag
Ala 435	-	expression tag
Asp 436	-	expression tag
Ser 437	-	expression tag
Thr 438	-	expression tag
Cys 439	-	expression tag
Tyr 440	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	315012.6
Branched	Number of molecules	7
	Total formula weight	3943.7
All*	Total formula weight	318956.3

*Water molecules are not included.