9EA0
Structure of the prefusion HKU5-19s Spike trimer (conformation 1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1365 | 150750.7 | 3 | UniProt (S4WWR5) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (A3EXD0) | Pipistrellus bat coronavirus HKU5 | S glycoprotein,E2,Peplomer protein |
| 2 | D, FA, R (D, f, R) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1600.4 | 3 | In PDB | |||
| 3 | AA, BA, CA, DA, E... (a, b, c, d, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 30 | In PDB GlyTouCan (G42666HT) | |||
| 4 | I, KA, W (I, k, W) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 5 | J, LA, X (J, l, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | EA, Q, SA (e, Q, s) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
| 7 | AB, BB, CB, IB, JB... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 8 | DB, EB, LB, MB, WA... (B, C, A) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 9 | FB, NB, YA (B, C, A) | FOLIC ACID | non-polymer | 441.4 | 3 | Chemie (FOL) | |||
| 10 | GB, HB, ZA (B, C, A) | LINOLEIC ACID | non-polymer | 280.4 | 3 | Chemie (EIC) | |||
| 11 | OB, PB, QB (A, B, C) | water | water | 18.0 | 1214 | Chemie (HOH) |
Sequence modifications
A, B, C: 22 - 1296 (UniProt: S4WWR5)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| Gly -9 | - | expression tag |
| Ile -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Met -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Val 10 | - | expression tag |
| Leu 11 | - | expression tag |
| Leu 12 | - | expression tag |
| Met 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Cys 15 | - | expression tag |
| Val 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Glu 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Thr 21 | - | expression tag |
| Pro 1058 | Thr 1058 | conflict |
| Pro 1059 | Val 1059 | conflict |
| Gly 1297 | - | expression tag |
| Ser 1298 | - | expression tag |
| Gly 1299 | - | expression tag |
| Tyr 1300 | - | expression tag |
| Ile 1301 | - | expression tag |
| Pro 1302 | - | expression tag |
| Glu 1303 | - | expression tag |
| Ala 1304 | - | expression tag |
| Pro 1305 | - | expression tag |
| Arg 1306 | - | expression tag |
| Asp 1307 | - | expression tag |
| Gly 1308 | - | expression tag |
| Gln 1309 | - | expression tag |
| Ala 1310 | - | expression tag |
| Tyr 1311 | - | expression tag |
| Val 1312 | - | expression tag |
| Arg 1313 | - | expression tag |
| Lys 1314 | - | expression tag |
| Asp 1315 | - | expression tag |
| Gly 1316 | - | expression tag |
| Glu 1317 | - | expression tag |
| Trp 1318 | - | expression tag |
| Val 1319 | - | expression tag |
| Leu 1320 | - | expression tag |
| Leu 1321 | - | expression tag |
| Ser 1322 | - | expression tag |
| Thr 1323 | - | expression tag |
| Phe 1324 | - | expression tag |
| Leu 1325 | - | expression tag |
| Gly 1326 | - | expression tag |
| Gly 1327 | - | expression tag |
| Ser 1328 | - | expression tag |
| Gly 1329 | - | expression tag |
| Leu 1330 | - | expression tag |
| Asn 1331 | - | expression tag |
| Asp 1332 | - | expression tag |
| Ile 1333 | - | expression tag |
| Phe 1334 | - | expression tag |
| Glu 1335 | - | expression tag |
| Ala 1336 | - | expression tag |
| Gln 1337 | - | expression tag |
| Lys 1338 | - | expression tag |
| Ile 1339 | - | expression tag |
| Glu 1340 | - | expression tag |
| Trp 1341 | - | expression tag |
| His 1342 | - | expression tag |
| Glu 1343 | - | expression tag |
| Gly 1344 | - | expression tag |
| Gly 1345 | - | expression tag |
| Ser 1346 | - | expression tag |
| His 1347 | - | expression tag |
| His 1348 | - | expression tag |
| His 1349 | - | expression tag |
| His 1350 | - | expression tag |
| His 1351 | - | expression tag |
| His 1352 | - | expression tag |
| His 1353 | - | expression tag |
| His 1354 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 452252.0 | |
| Branched | Number of molecules | 42 |
| Total formula weight | 24223.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4548.9 | |
| All* | Total formula weight | 481024.4 |
