9E70
Human XRN1 with Adenosine-3',5'-Bisphosphate (pAp) Bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5'-3' exoribonuclease 1 | polymer | 661 | 78101.6 | 2 | UniProt (Q8IZH2) Pfam (PF03159) Pfam (PF17846) | Homo sapiens (human) | Strand-exchange protein 1 homolog |
| 2 | C (A) | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (A3P) PubChem (73) PubChem (159296) PubChem (11796727) PubChem (13832521) PubChem (176478997) PubChem (46936223) PubChem (124507383) PubChem (57294977) PubChem (162468645) PubChem (92209390) PubChem (162966793) | |||
| 3 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | F, G, H, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 5 | T (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | U (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 7 | X, Y (A, B) | water | water | 18.0 | 723 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 653 (UniProt: Q8IZH2)
| PDB | External Database | Details |
|---|---|---|
| Asp 654 | - | expression tag |
| Tyr 655 | - | expression tag |
| Lys 656 | - | expression tag |
| Asp 657 | - | expression tag |
| Asp 658 | - | expression tag |
| Asp 659 | - | expression tag |
| Asp 660 | - | expression tag |
| Lys 661 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 156203.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1610.5 | |
| All* | Total formula weight | 157813.8 |
