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9E6S

BCL11A ZF4-6 with K784T Mutation in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
B-cell lymphoma/leukemia 11Apolymer10812444.22UniProt (Q9H165)
Pfam (PF00096)
Pfam (PF23611)
Homo sapiens (human)BCL-11A,B-cell CLL/lymphoma 11A,COUP-TF-interacting protein 1,Ecotropic viral integration site 9 protein homolog,EVI-9,Zinc finger protein 856
2B
(B)
DNA Strand Ipolymer206197.01Homo sapiens
3C
(C)
DNA Strand IIpolymer195763.81Homo sapiens
4E
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5F, G, H, I, J...
(A, D)
ZINC IONnon-polymer65.46Chemie (ZN)
PubChem (32051)
6L, M, N
(A, C, D)
waterwater18.09Chemie (HOH)
Sequence modifications
A, D: 730 - 835 (UniProt: Q9H165)
PDBExternal DatabaseDetails
Gly 728-expression tag
Ser 729-expression tag
Thr 784Lys 784engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight36849.3
Non-Polymers*Number of molecules7
Total formula weight454.5
All*Total formula weight37303.8
*Water molecules are not included.

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PDB entries from 2026-06-17

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