9E6K
Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | heavy chain of monoclonal antibody C12 | polymer | 216 | 23029.8 | 1 | Homo sapiens | ||
| 2 | B (L) | light chain monoclonal antibody C12 | polymer | 215 | 23440.0 | 1 | Homo sapiens | ||
| 3 | C (C) | Disintegrin and metalloproteinase domain-containing protein 17 | polymer | 115 | 12579.4 | 1 | UniProt (P78536) Pfam (PF00200) Pfam (PF16698) | Homo sapiens (human) | ADAM 17,Snake venom-like protease,TNF-alpha convertase,TNF-alpha-converting enzyme |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 59049.2 | |
| All* | Total formula weight | 59049.2 |
