9E4Z
GluA2-gamma2 complex bound glutamate and cyclothiazide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform Flip of Glutamate receptor 2 | polymer | 811 | 90967.7 | 4 | UniProt (P19491) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2 |
| 2 | E, F, G, H (E, F, G, H) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 208 | 23008.5 | 4 | UniProt (O88602) | Mus musculus (house mouse) | Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2 |
| 3 | I, L, O, P (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 4 | J, K, M, N (A, B) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) |
Sequence modifications
A, B, C, D: 10 - 820 (UniProt: P19491)
E, F, G, H: 1002 - 1207 (UniProt: O88602)
| PDB | External Database | Details |
|---|---|---|
| Glu 241 | Asn 256 | conflict |
| Leu 382 | Val 397 | conflict |
| - | Leu 399 | deletion |
| - | Thr 400 | deletion |
| - | Glu 401 | deletion |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| Glu 384 | Gly 405 | conflict |
| Asp 385 | Asn 406 | conflict |
| Gln 392 | Asn 413 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 1208 | - | expression tag |
| Gly 1209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 455904.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2148.0 | |
| All* | Total formula weight | 458052.7 |
