9E3P
Cryo-EM structure of the human P2X7 receptor in the UB-MBX-46-bound inhibited state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 595 | 68671.8 | 3 | UniProt (Q99572) Pfam (PF00864) Pfam (PF20478) | Homo sapiens (human) | P2X7,ATP receptor,P2Z receptor,Purinergic receptor |
| 2 | D, E, F, G, H... (E, F, G, H, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 3 | J, OA, Z (A, C, B) | (1s,3R,4R,6r,8S,9S)-N'-(2-chlorophenyl)-3,4,8,9-tetramethyltetracyclo[4.4.0.0~3,9~.0~4,8~]decane-1-carbohydrazide | non-polymer | 358.9 | 3 | Chemie (A1BD9) | |||
| 4 | AA, K, PA (B, A, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 5 | BA, CA, L, M, QA... (B, A, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 6 | DA, EA, N, O, SA... (B, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 7 | FA, GA, P, Q, UA... (B, A, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 8 | AB, BB, CB, HA, IA... (C, B, A) | PALMITIC ACID | non-polymer | 256.4 | 21 | Chemie (PLM) | Homo sapiens | ||
| 9 | Y (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 10 | DB, EB, FB (A, B, C) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 206015.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2546.4 | |
| Non-Polymers* | Number of molecules | 46 |
| Total formula weight | 12454.3 | |
| All* | Total formula weight | 221016.1 |
