9E3O
Cryo-EM structure of the human P2X7 receptor in the UB-ALT-P30-bound inhibited state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 595 | 68671.8 | 3 | UniProt (Q99572) Pfam (PF00864) Pfam (PF20478) | Homo sapiens (human) | P2X7,ATP receptor,P2Z receptor,Purinergic receptor |
| 2 | D, JA, T (A, C, B) | (3s,5s,7s)-N'-(2-chlorophenyl)adamantane-1-carbohydrazide | non-polymer | 304.8 | 3 | Chemie (A1BD8) | |||
| 3 | E, KA, U (A, C, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | F, G, LA, MA, V... (A, C, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | H, I, J, NA, OA... (A, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 6 | AA, BA, K, L, QA... (B, A, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 7 | CA, DA, EA, FA, GA... (B, A, C) | PALMITIC ACID | non-polymer | 256.4 | 21 | Chemie (PLM) | Homo sapiens | ||
| 8 | AB, BB, ZA (B, C, A) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 206015.5 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 12932.6 | |
| All* | Total formula weight | 218948.1 |
