9E1T
CryoEM structure of LARGE1 bound to UDP-GlcA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Xylosyl- and glucuronyltransferase LARGE1 | polymer | 770 | 89806.2 | 2 | UniProt (O95461) Pfam (PF01501) Pfam (PF13896) | Homo sapiens (human) | Acetylglucosaminyltransferase-like 1A,Glycosyltransferase-like protein,LARGE xylosyl- and glucuronyltransferase 1 |
| 2 | C, E (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, F (A, B) | URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | non-polymer | 580.3 | 2 | Chemie (UGA) |
Sequence modifications
A, B: 34 - 756 (UniProt: O95461)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ser -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Val 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Val 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Tyr 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Asp 11 | - | expression tag |
| His 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Asp 15 | - | expression tag |
| Tyr 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Asp 18 | - | expression tag |
| His 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Ile 21 | - | expression tag |
| Asp 22 | - | expression tag |
| Tyr 23 | - | expression tag |
| Lys 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Asp 27 | - | expression tag |
| Asp 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Ala 32 | - | expression tag |
| Ala 33 | - | expression tag |
| His 757 | - | expression tag |
| His 758 | - | expression tag |
| His 759 | - | expression tag |
| His 760 | - | expression tag |
| His 761 | - | expression tag |
| His 762 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 179612.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1270.4 | |
| All* | Total formula weight | 180882.9 |
