9E0I

Structure of the HKU5-19s RBD bound to the Bos taurus ACE2 receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme 2	polymer	766	89221.4	1	UniProt (Q58DD0) Pfam (PF01401) Pfam (PF16959)	Bos taurus (domestic cattle)	ACE-related carboxypeptidase
2	B (B)	Spike glycoprotein	polymer	267	29224.8	1	UniProt (S4WZQ4) Pfam (PF09408) UniProt (by SIFTS) (A3EXD0)	Pipistrellus bat coronavirus HKU5	S glycoprotein,E2,Peplomer protein
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D, E (D, E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G32152BH)
5	F, H, I (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	G (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7	J, K (A, B)	water	water		18.0	91	Chemie (HOH)

Sequence modifications

A: 1 - 739 (UniProt: Q58DD0)

PDB	External Database	Details
His 740	-	expression tag
His 741	-	expression tag
His 742	-	expression tag
His 743	-	expression tag
His 744	-	expression tag
His 745	-	expression tag
His 746	-	expression tag
His 747	-	expression tag
Gly 748	-	expression tag
Gly 749	-	expression tag
Ser 750	-	expression tag
Ser 751	-	expression tag
Gly 752	-	expression tag
Leu 753	-	expression tag
Asn 754	-	expression tag
Asp 755	-	expression tag
Ile 756	-	expression tag
Phe 757	-	expression tag
Glu 758	-	expression tag
Ala 759	-	expression tag
Gln 760	-	expression tag
Lys 761	-	expression tag
Ile 762	-	expression tag
Glu 763	-	expression tag
Trp 764	-	expression tag
His 765	-	expression tag
Glu 766	-	expression tag

B: 389 - 587 (UniProt: S4WZQ4)

PDB	External Database	Details
Met 358	-	expression tag
Gly 359	-	expression tag
Ile 360	-	expression tag
Leu 361	-	expression tag
Pro 362	-	expression tag
Ser 363	-	expression tag
Pro 364	-	expression tag
Gly 365	-	expression tag
Met 366	-	expression tag
Pro 367	-	expression tag
Ala 368	-	expression tag
Leu 369	-	expression tag
Leu 370	-	expression tag
Ser 371	-	expression tag
Leu 372	-	expression tag
Val 373	-	expression tag
Ser 374	-	expression tag
Leu 375	-	expression tag
Leu 376	-	expression tag
Ser 377	-	expression tag
Val 378	-	expression tag
Leu 379	-	expression tag
Leu 380	-	expression tag
Met 381	-	expression tag
Gly 382	-	expression tag
Cys 383	-	expression tag
Val 384	-	expression tag
Ala 385	-	expression tag
Glu 386	-	expression tag
Thr 387	-	expression tag
Gly 388	-	expression tag
Leu 588	-	expression tag
Val 589	-	expression tag
Pro 590	-	expression tag
Arg 591	-	expression tag
Gly 592	-	expression tag
Ser 593	-	expression tag
Ser 594	-	expression tag
Ser 595	-	expression tag
Gly 596	-	expression tag
Gly 597	-	expression tag
Ser 598	-	expression tag
Gly 599	-	expression tag
Leu 600	-	expression tag
Asn 601	-	expression tag
Asp 602	-	expression tag
Ile 603	-	expression tag
Phe 604	-	expression tag
Glu 605	-	expression tag
Ala 606	-	expression tag
Gln 607	-	expression tag
Lys 608	-	expression tag
Ile 609	-	expression tag
Glu 610	-	expression tag
Trp 611	-	expression tag
His 612	-	expression tag
Glu 613	-	expression tag
Gly 614	-	expression tag
Gly 615	-	expression tag
Ser 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118446.2
Branched	Number of molecules	3
	Total formula weight	1889.8
Non-Polymers*	Number of molecules	4
	Total formula weight	729.0
All*	Total formula weight	121065.0

*Water molecules are not included.