9DZN
KAT6A MYST domain complexed with a H3K14-CoA bisubstrate inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Histone H3K14 | polymer | 19 | 2033.4 | 1 | UniProt (Q6NXT2) | Homo sapiens | |
| 2 | B (A) | Histone acetyltransferase KAT6A | polymer | 286 | 33731.2 | 1 | UniProt (Q92794) Pfam (PF17772) Pfam (PF01853) | Homo sapiens (human) | MOZ,YBF2/SAS3,SAS2 and TIP60 protein 3,MYST-3,Monocytic leukemia zinc finger protein,Runt-related transcription factor-binding protein 2,Zinc finger protein 220 |
| 3 | C (C) | CARBOXYMETHYL COENZYME *A | non-polymer | 825.6 | 1 | Chemie (CMC) | synthetic construct | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F, G (C, A) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 501 - 784 (UniProt: Q92794)
| PDB | External Database | Details |
|---|---|---|
| Gly 499 | - | expression tag |
| Ser 500 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35764.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 983.1 | |
| All* | Total formula weight | 36747.6 |
