9DZK
Human GC-A bound to REGN5308
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (B, A) | Atrial natriuretic peptide receptor 1 | polymer | 1031 | 115702.8 | 2 | UniProt (P16066) | Homo sapiens (human) | Atrial natriuretic peptide receptor type A,ANP-A,ANPR-A,NPR-A,Guanylate cyclase A,GC-A |
| 2 | B (H) | REGN5308 - Heavy chain | polymer | 227 | 24468.4 | 1 | Mus musculus | ||
| 3 | C (L) | REGN5308 - Light chain | polymer | 213 | 23323.9 | 1 | Mus musculus | ||
| 4 | E, G (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F, H (D, F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | I, L (B, A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | J, K, M, N (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 8 | O (H) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
B, A: 0 - 1029 (UniProt: P16066)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 279198.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2021.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 955.7 | |
| All* | Total formula weight | 282175.6 |
