9DY4
Crystal structure of iron-bound human ADO C18S/C239S variant soaked in hydralazine at 2.39 Angstrom resolution
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2-aminoethanethiol dioxygenase | polymer | 274 | 30108.1 | 1 | UniProt (Q96SZ5) Pfam (PF07847) | Homo sapiens (human) | Cysteamine dioxygenase |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C (A) | 1-hydrazinophthalazine | non-polymer | 160.2 | 1 | Chemie (HLZ) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 2 - 270 (UniProt: Q96SZ5)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 18 | Cys 18 | engineered mutation |
| Ser 239 | Cys 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30108.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 400.2 | |
| All* | Total formula weight | 30508.3 |
