9DXU
Crystal structure of cobalt-incorporated human 2-aminoethanethiol (aka cysteamine) dioxygenase (ADO) variant C18S/C239S in complex with CP6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2-aminoethanethiol dioxygenase | polymer | 271 | 29841.8 | 1 | UniProt (Q96SZ5) Pfam (PF07847) | Homo sapiens (human) | Cysteamine dioxygenase |
| 2 | B (B) | CP6 | polymer | 16 | 1765.1 | 1 | synthetic construct | ||
| 3 | C (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G, H, I, J, K... (A, B) | THIOCYANATE ION | non-polymer | 58.1 | 10 | Chemie (SCN) | |||
| 6 | P (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 1 - 270 (UniProt: Q96SZ5)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ser 18 | Cys 18 | conflict |
| Ser 239 | Cys 239 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31606.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1038.2 | |
| All* | Total formula weight | 32645.1 |
