9DX7
LRRC8A:D Conformation 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, A, B, D) | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | polymer | 911 | 105530.1 | 4 | UniProt (Q80WG5) UniProt (P0ABE8) Pfam (PF12534) Pfam (PF07361) Pfam (PF13855) Pfam (PF23598) | Mus musculus (house mouse) | Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo,Cytochrome b-562 |
| 2 | E, F (E, F) | Volume-regulated anion channel subunit LRRC8D | polymer | 868 | 99317.9 | 2 | UniProt (Q8BGR2) Pfam (PF12534) Pfam (PF13855) | Mus musculus (house mouse) | Leucine-rich repeat-containing protein 5,Leucine-rich repeat-containing protein 8D |
| 3 | G, H, I, J, K... (C, A, B, D, E...) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 18 | Chemie (PEE) PubChem (108229) PubChem (44891344) PubChem (54095275) PubChem (14238554) PubChem (5909904) PubChem (9546757) PubChem (6437392) PubChem (99655478) PubChem (99655479) PubChem (9546744) PubChem (138113035) PubChem (171729549) |
Sequence modifications
C, A, B, D: 1 - 68 (UniProt: Q80WG5)
C, A, B, D: 68 - 72 (UniProt: P0ABE8)
C, A, B, D: 72 - 810 (UniProt: Q80WG5)
E, F: 1 - 859 (UniProt: Q8BGR2)
C, A, B, D: 68 - 72 (UniProt: P0ABE8)
| PDB | External Database | Details |
|---|---|---|
| Trp 68 | Met 29 | conflict |
| Ile 68 | Val 39 | conflict |
| Ala 72 | Ser 122 | conflict |
| Ile 72 | His 124 | conflict |
| Gln 72 | Lys 125 | conflict |
| Leu 72 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 811 | - | expression tag |
| Asn 812 | - | expression tag |
| Ser 813 | - | expression tag |
| Leu 814 | - | expression tag |
| Glu 815 | - | expression tag |
| Val 816 | - | expression tag |
| Leu 817 | - | expression tag |
| Phe 818 | - | expression tag |
| Gln 819 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 860 | - | expression tag |
| Asn 861 | - | expression tag |
| Ser 862 | - | expression tag |
| Glu 863 | - | expression tag |
| Asn 864 | - | expression tag |
| Leu 865 | - | expression tag |
| Tyr 866 | - | expression tag |
| Phe 867 | - | expression tag |
| Gln 868 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 620756.1 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 13392.6 | |
| All* | Total formula weight | 634148.8 |
