9DWV
Ternary complex of CRBN-DDB1-PPIL4 RRM domain with FPFT-2216
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF23726) Pfam (PF03178) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 2 | B (B) | Protein cereblon | polymer | 444 | 50747.8 | 1 | UniProt (Q96SW2) Pfam (PF02190) Pfam (PF03226) | Homo sapiens (human) | |
| 3 | C (C) | Peptidyl-prolyl cis-trans isomerase-like 4 | polymer | 82 | 9624.9 | 1 | UniProt (Q8WUA2) Pfam (PF00076) | Homo sapiens (human) | PPIase,Cyclophilin-like protein PPIL4,Rotamase PPIL4 |
| 4 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (B) | (3S)-3-[(4M)-4-(4-methoxythiophen-3-yl)-1H-1,2,3-triazol-1-yl]piperidine-2,6-dione | non-polymer | 292.3 | 1 | Chemie (A1BC8) |
Sequence modifications
B: 1 - 442 (UniProt: Q96SW2)
C: 240 - 318 (UniProt: Q8WUA2)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 237 | - | expression tag |
| Gly 238 | - | expression tag |
| Arg 239 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 187470.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 357.7 | |
| All* | Total formula weight | 187827.9 |
