9DWE
Cryo-EM structure of hemagglutinin H5 A/Texas/37/2024 in complex with LSTa and antibody CR9114
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (L, M, N) | CR9114 Fab light chain | polymer | 110 | 11482.6 | 3 | Homo sapiens | ||
| 2 | B, E, H (H, I, J) | CR9114 Fab Fab heavy chain | polymer | 120 | 12911.3 | 3 | Homo sapiens | ||
| 3 | C, F, I (A, B, C) | Hemagglutinin | polymer | 572 | 65198.4 | 3 | UniProt (A0A8E4ZAK5) | Influenza A virus | |
| 4 | J, K, L (P, D, E) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 3 | In PDB GlyTouCan (G30207PZ) | |||
| 5 | AA, M, N, O, P... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
A, B, C: -5 - 507 (UniProt: A0A8E4ZAK5)
| PDB | External Database | Details |
|---|---|---|
| Met 111 | Leu 120 | conflict |
| Gln 122 | Leu 131 | conflict |
| Ile 199 | Thr 211 | conflict |
| Ala 214 | Val 226 | conflict |
| Ser 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Tyr 510 | - | expression tag |
| Ile 511 | - | expression tag |
| Pro 512 | - | expression tag |
| Glu 513 | - | expression tag |
| Ala 514 | - | expression tag |
| Pro 515 | - | expression tag |
| Arg 516 | - | expression tag |
| Asp 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gln 519 | - | expression tag |
| Ala 520 | - | expression tag |
| Tyr 521 | - | expression tag |
| Val 522 | - | expression tag |
| Arg 523 | - | expression tag |
| Lys 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Gly 526 | - | expression tag |
| Glu 527 | - | expression tag |
| Trp 528 | - | expression tag |
| Val 529 | - | expression tag |
| Leu 530 | - | expression tag |
| Leu 531 | - | expression tag |
| Ser 532 | - | expression tag |
| Thr 533 | - | expression tag |
| Phe 534 | - | expression tag |
| Leu 535 | - | expression tag |
| Gly 536 | - | expression tag |
| Ser 537 | - | expression tag |
| Gly 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Asn 540 | - | expression tag |
| Asp 541 | - | expression tag |
| Ile 542 | - | expression tag |
| Phe 543 | - | expression tag |
| Glu 544 | - | expression tag |
| Ala 545 | - | expression tag |
| Gln 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Ile 548 | - | expression tag |
| Glu 549 | - | expression tag |
| Trp 550 | - | expression tag |
| His 551 | - | expression tag |
| Glu 552 | - | expression tag |
| Gly 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 268776.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1414.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 273509.0 |
