9DVR

Cryo-EM structure of Human Fibroblast Activation Protein alpha dimer with two SUMO-I3 VHHs bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Antiplasmin-cleaving enzyme FAP, soluble form	polymer	747	86516.2	2	UniProt (Q12884) Pfam (PF00930) Pfam (PF00326)	Homo sapiens (human)	APCE
2	C, D (G, H)	SUMO-I3	polymer	240	26438.3	2	Pfam (PF00240) UniProt (by SIFTS) (Q12306)	Lama glama
3	E, F, G, H, I... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)

Sequence modifications

A, B: 27 - 760 (UniProt: Q12884)

PDB	External Database	Details
Thr 761	-	expression tag
Gly 762	-	expression tag
His 763	-	expression tag
His 764	-	expression tag
His 765	-	expression tag
His 766	-	expression tag
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
Gly 771	-	expression tag
Gly 772	-	expression tag
Gln 773	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	225909.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1769.7
All*	Total formula weight	227678.7

*Water molecules are not included.