9DU0
Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a SMARCA-BD binder
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Isoform Short of Probable global transcription activator SNF2L2 | polymer | 120 | 13991.1 | 3 | UniProt (P51531) Pfam (PF00439) | Homo sapiens (human) | ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| 2 | D, F (A, B) | (2P)-2-[(6aS,11R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1',2':4,5]pyrazino[2,3-c]pyridazin-2-yl]phenol | non-polymer | 283.3 | 2 | Chemie (A1BB5) PubChem (156539772) PubChem (156562200) PubChem (156562337) | |||
| 3 | E, G, H (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B, C: 1373 - 1491 (UniProt: P51531)
| PDB | External Database | Details |
|---|---|---|
| Ser 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41973.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 762.9 | |
| All* | Total formula weight | 42736.2 |
