9DTU
Structure of the Measles virus Fusion protein ectodomain E170G E455G with mutated furin cleavage site in the pre-fusion conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fusion glycoprotein F0 | polymer | 529 | 56819.9 | 3 | UniProt (Q786F3) Pfam (PF00523) | Measles virus strain Ichinose-B95a | |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 3 | J, K, L (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | M, N, O (A, B, C) | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 495 (UniProt: Q786F3)
| PDB | External Database | Details |
|---|---|---|
| Asn 109 | Arg 109 | engineered mutation |
| Asn 111 | Lys 111 | engineered mutation |
| Gly 170 | Glu 170 | engineered mutation |
| Gly 455 | Glu 455 | engineered mutation |
| Gly 496 | - | expression tag |
| Gly 497 | - | expression tag |
| Gly 498 | - | expression tag |
| Ser 499 | - | expression tag |
| Gly 500 | - | expression tag |
| Gly 501 | - | expression tag |
| Trp 502 | - | expression tag |
| Ser 503 | - | expression tag |
| His 504 | - | expression tag |
| Pro 505 | - | expression tag |
| Gln 506 | - | expression tag |
| Phe 507 | - | expression tag |
| Glu 508 | - | expression tag |
| Lys 509 | - | expression tag |
| Gly 510 | - | expression tag |
| Gly 511 | - | expression tag |
| Gly 512 | - | expression tag |
| Ser 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Gly 516 | - | expression tag |
| Ser 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Trp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| His 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Phe 527 | - | expression tag |
| Glu 528 | - | expression tag |
| Lys 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 170459.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2546.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 173669.6 |
