9DTQ
The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone deacetylase 2 | polymer | 487 | 55312.0 | 1 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (human) | HD2,Protein deacylase HDAC2 |
| 2 | B, D (B, E) | Kelch repeat and BTB domain-containing protein 4 | polymer | 520 | 58463.1 | 2 | UniProt (Q9NVX7) Pfam (PF00651) Pfam (PF07707) Pfam (PF07646) | Homo sapiens (human) | BTB and kelch domain-containing protein 4 |
| 3 | C (D) | REST corepressor 1 | polymer | 401 | 45974.4 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) | Homo sapiens (human) | Protein CoREST |
| 4 | E (D) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) |
Sequence modifications
B, E: 17 - 536 (UniProt: Q9NVX7)
D: -18 - 381 (UniProt: Q9UKL0)
| PDB | External Database | Details |
|---|---|---|
| Pro 311 | - | insertion |
| Arg 312 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 218212.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 660.0 | |
| All* | Total formula weight | 218872.6 |
