9DQ5

Crystal structure of Anti-CTLA-4 Fab (9D9) in complex with mouse CTLA-4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G (H, I, J)	9D9 heavy chain	polymer	228	24612.5	3		Homo sapiens (human)
2	B, E, H (L, M, N)	9D9 light chain	polymer	219	24013.8	3		Homo sapiens (human)
3	C, F (C, D)	Cytotoxic T-lymphocyte protein 4	polymer	135	15029.7	2	UniProt (P09793) Pfam (PF07686)	Mus musculus (mouse)	Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4

Sequence modifications

C, D: -2 - 116 (UniProt: P09793)

PDB	External Database	Details
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	175938.3
All*	Total formula weight	175938.3

*Water molecules are not included.