9DPF
Crystal structure of TMPRSS11D S368A complexed with its own zymogen activation motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Transmembrane protease serine 11D | polymer | 232 | 25318.5 | 2 | UniProt (O60235) Pfam (PF00089) | Homo sapiens (human) | Airway trypsin-like protease |
| 2 | B, D (B, D) | Transmembrane protease serine 11D non-catalytic chain | polymer | 18 | 1930.2 | 2 | UniProt (O60235) | Homo sapiens (human) | |
| 3 | E, F (C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A, C: 187 - 418 (UniProt: O60235)
| PDB | External Database | Details |
|---|---|---|
| Ala 368 | Ser 368 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54497.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 124.1 | |
| All* | Total formula weight | 54621.4 |
